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Plant Physiol, June 2001, Vol. 126, pp. 811-825
Genetic Control of Natural Variation in Arabidopsis Glucosinolate
Accumulation
Daniel J.
Kliebenstein,
Juergen
Kroymann,
Paul
Brown,
Antje
Figuth,
Deana
Pedersen,
Jonathan
Gershenzon, and
Thomas
Mitchell-Olds*
Departments of Genetics and Evolution (D.J.K., J.K., A.F., D.P.,
T.M.-O.) and Plant Biochemistry (P.B., J.G.), Max Planck Institute of
Chemical Ecology, Carl Zeiss Promenade 10, 07745 Jena, Germany
Glucosinolates are biologically active secondary metabolites of the
Brassicaceae and related plant families that influence plant/insect
interactions. Specific glucosinolates can act as feeding deterrents or
stimulants, depending upon the insect species. Hence, natural selection
might favor the presence of diverse glucosinolate profiles within a
given species. We determined quantitative and qualitative variation in
glucosinolates in the leaves and seeds of 39 Arabidopsis ecotypes. We
identified 34 different glucosinolates, of which the majority are
chain-elongated compounds derived from methionine. Polymorphism at only
five loci was sufficient to generate 14 qualitatitvely different leaf
glucosinolate profiles. Thus, there appears to be a modular genetic
system regulating glucosinolate profiles in Arabidopsis. This system
allows the rapid generation of new glucosinolate combinations in
response to changing herbivory or other selective pressures. In
addition to the qualitative variation in glucosinolate profiles, we
found a nearly 20-fold difference in the quantity of total aliphatic
glucosinolates and were able to identify a single locus that controls
nearly three-quarters of this variation.
*
Corresponding author; e-mail tmo{at}ice.mpg.de; fax
49-3641-643668.
© 2001 American Society of Plant Physiologists
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