Plant Physiol. Illumina
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Web of Science (25)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Lange, B. M.
Right arrow Articles by Croteau, R. B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lange, B. M.
Right arrow Articles by Croteau, R. B.
Agricola
Right arrow Articles by Lange, B. M.
Right arrow Articles by Croteau, R. B.

Plant Physiol, September 2001, Vol. 127, pp. 305-314

Isoprenoid Biosynthesis. Metabolite Profiling of Peppermint Oil Gland Secretory Cells and Application to Herbicide Target Analysis1

B. Markus Lange,2 Raymond E.B. Ketchum, and Rodney B. Croteau*

Institute of Biological Chemistry, Washington State University, Pullman, Washington 99164-6340

Two independent pathways operate in plants for the synthesis of isopentenyl diphosphate and dimethylallyl diphosphate, the central intermediates in the biosynthesis of all isoprenoids. The mevalonate pathway is present in the cytosol, whereas the recently discovered mevalonate-independent pathway is localized to plastids. We have used isolated peppermint (Mentha piperita) oil gland secretory cells as an experimental model system to study the effects of the herbicides fosmidomycin, phosphonothrixin, methyl viologen, benzyl viologen, clomazone, 2-(dimethylamino)ethyl diphosphate, alendronate, and pamidronate on the pools of metabolites related to monoterpene biosynthesis via the mevalonate-independent pathway. A newly developed isolation protocol for polar metabolites together with an improved separation and detection method based on liquid chromatography-mass spectrometry have allowed assessment of the enzyme targets for a number of these herbicides.

1 This work was supported by a grant from the U.S. Department of Energy.

2 Present address: Torrey Mesa Research Institute, Syngenta, Research and Technology, 3115 Merryfield Row, San Diego, CA 92121-1125.

* Corresponding author; e-mail croteau{at}mail.wsu.edu; fax 509-335-7643.

© 2001 American Society of Plant Physiologists


This article has been cited by other articles:


Home page
 Plant CellHome page
E. Gerber, A. Hemmerlin, M. Hartmann, D. Heintz, M.-A. Hartmann, J. Mutterer, M. Rodriguez-Concepcion, A. Boronat, A. Van Dorsselaer, M. Rohmer, et al.
The Plastidial 2-C-Methyl-D-Erythritol 4-Phosphate Pathway Provides the Isoprenyl Moiety for Protein Geranylgeranylation in Tobacco BY-2 Cells
PLANT CELL, January 1, 2009; 21(1): 285 - 300.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
T. A. Walsh, T. Bauer, R. Neal, A. O. Merlo, P. R. Schmitzer, G. R. Hicks, M. Honma, W. Matsumura, K. Wolff, and J. P. Davies
Chemical Genetic Identification of Glutamine Phosphoribosylpyrophosphate Amidotransferase as the Target for a Novel Bleaching Herbicide in Arabidopsis
Plant Physiology, July 1, 2007; 144(3): 1292 - 1304.
[Abstract] [Full Text] [PDF]

Home page
 J Exp BotHome page
F. Carrari and A. R. Fernie
Metabolic regulation underlying tomato fruit development
J. Exp. Bot., June 1, 2006; 57(9): 1883 - 1897.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
I. Nogues, F. Brilli, and F. Loreto
Dimethylallyl Diphosphate and Geranyl Diphosphate Pools of Plant Species Characterized by Different Isoprenoid Emissions
Plant Physiology, June 1, 2006; 141(2): 721 - 730.
[Abstract] [Full Text] [PDF]

Home page
 J Exp BotHome page
D. Lemenager, L. Ouelhazi, S. Mahroug, B. Veau, B. St-Pierre, M. Rideau, J. Aguirreolea, V. Burlat, and M. Clastre
Purification, molecular cloning, and cell-specific gene expression of the alkaloid-accumulation associated protein CrPS in Catharanthus roseus
J. Exp. Bot., April 1, 2005; 56(414): 1221 - 1228.
[Abstract] [Full Text] [PDF]

Home page
 Plant Cell PhysiolHome page
K. Morino, F. Matsuda, H. Miyazawa, A. Sukegawa, H. Miyagawa, and K. Wakasa
Metabolic Profiling of Tryptophan-overproducing Rice Calli that Express a Feedback-insensitive {alpha} Subunit of Anthranilate Synthase
Plant Cell Physiol., March 1, 2005; 46(3): 514 - 521.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
E. von Roepenack-Lahaye, T. Degenkolb, M. Zerjeski, M. Franz, U. Roth, L. Wessjohann, J. Schmidt, D. Scheel, and S. Clemens
Profiling of Arabidopsis Secondary Metabolites by Capillary Liquid Chromatography Coupled to Electrospray Ionization Quadrupole Time-of-Flight Mass Spectrometry
Plant Physiology, February 1, 2004; 134(2): 548 - 559.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
H. P. Affek and D. Yakir
Natural Abundance Carbon Isotope Composition of Isoprene Reflects Incomplete Coupling between Isoprene Synthesis and Photosynthetic Carbon Flow
Plant Physiology, April 1, 2003; 131(4): 1727 - 1736.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
M. Rodriguez-Concepcion and A. Boronat
Elucidation of the Methylerythritol Phosphate Pathway for Isoprenoid Biosynthesis in Bacteria and Plastids. A Metabolic Milestone Achieved through Genomics
Plant Physiology, November 1, 2002; 130(3): 1079 - 1089.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ASPB Publications PLANT PHYSIOLOGY® THE PLANT CELL
Copyright © 2001 by the American Society of Plant Biologists