Plant Physiol. Illumina
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Web of Science (36)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Shapiro, A. D.
Right arrow Articles by Zhang, C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Shapiro, A. D.
Right arrow Articles by Zhang, C.
Agricola
Right arrow Articles by Shapiro, A. D.
Right arrow Articles by Zhang, C.

Plant Physiol, November 2001, Vol. 127, pp. 1089-1101

The Role of NDR1 in Avirulence Gene-Directed Signaling and Control of Programmed Cell Death in Arabidopsis1

Allan D. Shapiro* and Chu Zhang

Delaware Agricultural Experiment Station, Department of Plant and Soil Sciences, College of Agriculture and Natural Resources, University of Delaware, Newark, Delaware 19717-1303

Arabidopsis plants containing the ndr1-1 mutation are incapable of mounting a hypersensitive response to bacteria carrying avrRpt2, but show an exaggerated cell death response to bacteria carrying avrB (Century et al., 1995). We show here that ndr1-1 plants are severely impaired in induction of systemic acquired resistance and PR1-driven transcription of a reporter gene in response to Pseudomonas syringae strains carrying avrRpt2 but not in response to P. syringae carrying avrB. The ndr1-1 mutation also impaired salicylic acid (SA) accumulation in response to treatments that produced reactive oxygen species (ROS) and impaired induction of systemic acquired resistance in response to in situ production of ROS. Hydrogen peroxide accumulated in wild-type Arabidopsis leaves beginning 4 to 7 h postinoculation with P. syringae carrying either avrRpt2 or avrB. In ndr1-1 plants, P. syringae carrying avrRpt2 elicited no detectable hydrogen peroxide production. Hydrogen peroxide production in response to bacteria carrying avrB was similar to that of Columbia in kinetics but of lesser intensity at early time points. These data are interpreted to indicate that NDR1 links ROS generation to SA production and that the phenotypic consequences of the ndr1-1 mutation are caused by a reduced ability to accumulate SA upon pathogen infection.

1 This project was initiated when A.D.S. was a National Institutes of Health postdoctoral fellow in the lab of Brian J. Staskawicz (University of California, Berkeley). This work was subsequently supported by the University of Delaware (start-up funds to A.D.S.) and by the College of Agriculture and Natural Resources, University of Delaware (predoctoral research assistantship to C.Z.). This is paper no. 1,694 in the Journal Series of the Delaware Agricultural Experiment Station.

* Corresponding author; e-mail ashapiro{at}udel.edu; fax 302-831-3409.

© 2001 American Society of Plant Physiologists


This article has been cited by other articles:


Home page
 Plant CellHome page
E. Attaran, T. E. Zeier, T. Griebel, and J. Zeier
Methyl Salicylate Production and Jasmonate Signaling Are Not Essential for Systemic Acquired Resistance in Arabidopsis
PLANT CELL, March 1, 2009; 21(3): 954 - 971.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
T. Rudrappa, K. J. Czymmek, P. W. Pare, and H. P. Bais
Root-Secreted Malic Acid Recruits Beneficial Soil Bacteria
Plant Physiology, November 1, 2008; 148(3): 1547 - 1556.
[Abstract] [Full Text] [PDF]

Home page
 J Exp BotHome page
M.-H. Weech, M. Chapleau, L. Pan, C. Ide, and J. C. Bede
Caterpillar saliva interferes with induced Arabidopsis thaliana defence responses via the systemic acquired resistance pathway
J. Exp. Bot., June 1, 2008; 59(9): 2437 - 2448.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
A. A. Gust, R. Biswas, H. D. Lenz, T. Rauhut, S. Ranf, B. Kemmerling, F. Gotz, E. Glawischnig, J. Lee, G. Felix, et al.
Bacteria-derived Peptidoglycans Constitute Pathogen-associated Molecular Patterns Triggering Innate Immunity in Arabidopsis
J. Biol. Chem., November 2, 2007; 282(44): 32338 - 32348.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
K. Yoshioka, W. Moeder, H.-G. Kang, P. Kachroo, K. Masmoudi, G. Berkowitz, and D. F. Klessig
The Chimeric Arabidopsis CYCLIC NUCLEOTIDE-GATED ION CHANNEL11/12 Activates Multiple Pathogen Resistance Responses
PLANT CELL, March 1, 2006; 18(3): 747 - 763.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
D. Takemoto, A. R. Hardham, and D. A. Jones
Differences in Cell Death Induction by Phytophthora Elicitins Are Determined by Signal Components Downstream of MAP Kinase Kinase in Different Species of Nicotiana and Cultivars of Brassica rapa and Raphanus sativus
Plant Physiology, July 1, 2005; 138(3): 1491 - 1504.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
J. Cui, A. K. Bahrami, E. G. Pringle, G. Hernandez-Guzman, C. L. Bender, N. E. Pierce, and F. M. Ausubel
Pseudomonas syringae manipulates systemic plant defenses against pathogens and herbivores
PNAS, February 1, 2005; 102(5): 1791 - 1796.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
S. Lorrain, B. Lin, M. C. Auriac, T. Kroj, P. Saindrenan, M. Nicole, C. Balague, and D. Roby
VASCULAR ASSOCIATED DEATH1, a Novel GRAM Domain-Containing Protein, Is a Regulator of Cell Death and Defense Responses in Vascular Tissues
PLANT CELL, August 1, 2004; 16(8): 2217 - 2232.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
C. A. Wright and G. A. Beattie
Pseudomonas syringae pv. tomato cells encounter inhibitory levels of water stress during the hypersensitive response of Arabidopsis thaliana
PNAS, March 2, 2004; 101(9): 3269 - 3274.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
J. T. Song, H. Lu, and J. T. Greenberg
Divergent Roles in Arabidopsis thaliana Development and Defense of Two Homologous Genes, ABERRANT GROWTH AND DEATH2 and AGD2-LIKE DEFENSE RESPONSE PROTEIN1, Encoding Novel Aminotransferases
PLANT CELL, February 1, 2004; 16(2): 353 - 366.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
H. Lu, D. N. Rate, J. T. Song, and J. T. Greenberg
ACD6, a Novel Ankyrin Protein, Is a Regulator and an Effector of Salicylic Acid Signaling in the Arabidopsis Defense Response
PLANT CELL, October 1, 2003; 15(10): 2408 - 2420.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
A. Varet, B. Hause, G. Hause, D. Scheel, and J. Lee
The Arabidopsis NHL3 Gene Encodes a Plasma Membrane Protein and Its Overexpression Correlates with Increased Resistance to Pseudomonas syringae pv. tomato DC3000
Plant Physiology, August 1, 2003; 132(4): 2023 - 2033.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
Y. Tao, Z. Xie, W. Chen, J. Glazebrook, H.-S. Chang, B. Han, T. Zhu, G. Zou, and F. Katagiri
Quantitative Nature of Arabidopsis Responses during Compatible and Incompatible Interactions with the Bacterial Pathogen Pseudomonas syringae
PLANT CELL, February 1, 2003; 15(2): 317 - 330.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
P. Tornero, P. Merritt, A. Sadanandom, K. Shirasu, R. W. Innes, and J. L. Dangl
RAR1 and NDR1 Contribute Quantitatively to Disease Resistance in Arabidopsis, and Their Relative Contributions Are Dependent on the R Gene Assayed
PLANT CELL, May 1, 2002; 14(5): 1005 - 1015.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ASPB Publications PLANT PHYSIOLOGY® THE PLANT CELL
Copyright © 2001 by the American Society of Plant Biologists