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Plant Physiol, June 2002, Vol. 129, pp. 500-515

Two-Component Signal Transduction Pathways in Arabidopsis1

Ildoo Hwang, Huei-Chi Chen, and Jen Sheen*

Department of Genetics, Harvard Medical School, Boston, Massachusetts 02114; and Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts 02114

The two-component system, consisting of a histidine (His) protein kinase that senses a signal input and a response regulator that mediates the output, is an ancient and evolutionarily conserved signaling mechanism in prokaryotes and eukaryotes. The identification of 54 His protein kinases, His-containing phosphotransfer proteins, response regulators, and related proteins in Arabidopsis suggests an important role of two-component phosphorelay in plant signal transduction. Recent studies indicate that two-component elements are involved in plant hormone, stress, and light signaling. In this review, we present a genome analysis of the Arabidopsis two-component elements and summarize the major advances in our understanding of Arabidopsis two-component signaling.

1 This work was supported by the National Science Foundation (grant nos. IBN9723610 and DBI007692) and by the National Institutes of Health (grant no. GM60493).

* Corresponding author; e-mail sheen{at}molbio.mgh.harvard.edu; fax 617-726-6893.

© 2002 American Society of Plant Physiologists


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[Abstract] [Full Text] [PDF]

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[Abstract] [Full Text] [PDF]

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