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Articles

The Biosynthesis of -Aminolevulinic Acid in Chlorella¹

^a Department of Botanical Sciences, University of California, Los Angeles, California 90024

When autotrophically growing cultures of Chlorella are treated with levulinic acid, -aminolevulinic acid is excreted into the medium, providing a direct demonstration of -aminolevulinic acid production in a green plant. Evidence is presented which indicates that -aminolevulinic acid formation may be the the rate-controlling step of chlorophyll synthesis in Chlorella, and that control of the rate of -aminolevulinic acid synthesis may be exerted at the level of production and breakdown of an enzyme which catalyzes its formation.

¹ Supported by United States Public Health Service Predoctoral Fellowship GM-28419.

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