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Plant Physiology 52:246-247 (1973)
© 1973 American Society of Plant Biologists

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Articles

Triparanol Inhibition of Sterol Biosynthesis in Chlorella ellipsoidea1,2

J. T. Chan and G. W. Patterson

a Department of Botany, University of Maryland, College Park, Maryland 20742

The sterol composition of C. ellipsoidea was markedly changed when this alga was grown in the presence of 1 µg/g triparanol. Triparanol appears to inhibit the removal of 14{alpha}-methyl group, the second alkylation at C-24, {Delta}7-reductase, and {Delta}8 -> {Delta}7-isomerase. The effect of triparanol in Chlorella is much more diversified than the specific effect originally assigned to it in animals.

1 This work was supported in part by a grant from the National Aeronautics and Space Administration.

2 Scientific Article No. A1839 Contribution No. 4747 of the Maryland Agricultural Experimental Station.






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