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Plant Physiology 54:368-371 (1974) © 1974 American Society of Plant Biologists myo-Inositol 1-Phosphate Synthase Inhibition and Control of Uridine Diphosphate-D-glucuronic Acid Biosynthesis in Plants 1,2a Department of Biology, State University of New York at Buffalo, Buffalo, New York 14214
Of the eight intermediates associated with the two pathways of UDP-D-glucuronic acid biosynthesis found in plants, only D-glucuronic acid inhibited myo-inositol 1-phosphate synthase (EC 5.5.1.4), formerly referred to as D-glucose 6-phosphate cycloaldolase. Inhibition was competitive. An attempt to demonstrate over-all reversibility of the synthase indicated that it was less than 5% reversible, if at all.
1 This work was supported by Grant GM-12422 from the National Institutes of Health. 2 This work is dedicated to Professor Otto Hoffmann-Ostenhof on the occasion of his 60th birthday.
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