Plant Physiol. Journal of Pharmacology and Experimental Therapeutics
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Plant Physiology 68:1244-1248 (1981)
© 1981 American Society of Plant Biologists

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Articles

Temperature Compensation of Circadian Period Length in Clock Mutants of Neurospora crassa1

George F. Gardner and Jerry F. Feldman2

Thimann Laboratories, University of California at Santa Cruz, Santa Cruz, California 95064

Temperature compensation of circadian period length in 12 clock mutants of Neurospora crassa has been examined at temperatures between 16 and 34°C. In the wild-type strain, below 30°C (the "breakpoint" temperature), the clock is well-compensated (Q10 = 1), while above 30°C, the clock is less well-compensated (Q10 = 1.3). For mutants at the frq locus, mutations that shorten the circadian period length (frq-1, frq-2, frq-4, and frq-6) do not alter this temperature compensation response. In long period frq mutants (frq-3, frq-7, frq-8), however, the breakpoint temperature is lowered, and the longer the period length of the mutants the lower the breakpoint temperature. Long period mutants at other loci exhibit other types of alterations in temperature compensation—e.g. chr is well-compensated even above 30°C, while prd-3 has a Q10 significantly less than 1 below 30°C. Prd-4, a short period mutant, has several breakpoint temperatures. Among four double mutants examined, the only unusual interaction between the individual mutations occurred with chr prd, which had an unusually low Q10 value of 0.86 below 27°C. There was no correlation between circadian period length and growth rate. These strains should be useful tools to test models for the temperature compensation mechanism.

2 To whom reprint requests should be sent.

1 Supported by Grant GM-22144 from the National Institute of General Medical Sciences.




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