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Plant Physiology 83:726-727 (1987)
© 1987 American Society of Plant Biologists

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Metabolism and Enzymology

Cytokinin Utilization by Adenine-Requiring Mutants of the Yeast Saccharomyces cerevisiae1

Carol A. Van Kast2 and Howard M. Laten

Department of Biology, Loyola University of Chicago, 6525 N. Sheridan Road, Chicago, Illinois 60626

By monitoring the growth of several adenine auxotrophs of the yeast Saccharomyces cerevisiae on cytokinin-supplemented media, we have demonstrated that this organism can utilize some of these derivatives as a source of adenine. Growth of a mutant lacking adenylosuccinate synthetase suggests that the conversion of cytokinins to adenine does not involve a hypoxanthine intermediate and may be catalyzed by an enzyme analogous to cytokinin oxidase.

2 Present address: Abbott Laboratories, Pharmaceutical Products Division, Abbott Park, IL 60064.

1 Supported by NIH grant GM31023 to H. M. L.






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Copyright © 1987 by the American Society of Plant Biologists