Plant Physiology 90:13-16 (1989)
© 1989 American Society of Plant Biologists
Metabolism and Enzymology
An Assessment of the Rubisco Inhibitor
2-Carboxyarabinitol-1-Phosphate and D-Hamamelonic Acid 21-Phosphate Are Identical Compounds
Erwin Beck,
Renate Scheibe and
Josef Reiner
Lehrstuhl Pflanzenphysiologie, Universität Bayreuth, D 8580 Bayreuth, Federal Republic of Germany,
Lehrstuhl Organische Chemie I, Universität Bayreuth, D 8580 Bayreuth, Federal Republic of Germany
2-Carboxyarabinitol-1-phosphate, the nocturnal inhibitor of ribulose-1,5-bisphosphate carboxylase/oxygenase is identical with D-hamamelonic acid-21-phosphate. Reasoning is based on theoretical considerations as well as on mass spectra and 1H- and 13C-NMR spectra of the phosphate-free compounds. D-Hamamelonic acid-21-phosphate is interpreted as a metabolic derivative of D-hamamelose-21,5-bisphosphate which originates in the chloroplast from fructose-1,6-bisphosphate. A simple method for the synthesis of the inhibitor is suggested.
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