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Cellular and Structural Biology

Monoclonal Antibodies against Pectin

Recognition of a Conformation Induced by Calcium

Unité de Biotechnologie théorique, Facultés Universitaires de Namur, Rue de Bruxelles 61, B-5000 Namur, Belgium, Laboratoire d'Immunologie et de Microbiologie, Facultés Universitaires de Namur, Rue de Bruxelles 61, B-5000 Namur, Belgium

Monoclonal antibodies have been produced that recognize a conformation of homopolygalacturonic acid (pectic acid) induced by an optimum concentration of calcium and sodium of about 1 and 150 millinormal, respectively. The epitope recognized is probably part of the dimers of pectin chains associated according to the `egg box' model.

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