Plant Physiol.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Plant Physiology 92:1081-1085 (1990)
© 1990 American Society of Plant Biologists

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Web of Science (43)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Haughn, G. W.
Right arrow Articles by Somerville, C. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Haughn, G. W.
Right arrow Articles by Somerville, C. R.
Agricola
Right arrow Articles by Haughn, G. W.
Right arrow Articles by Somerville, C. R.
Metabolism and Enzymology

A Mutation Causing Imidazolinone Resistance Maps to the Csr1 Locus of Arabidopsis thaliana1

George W. Haughn and Christopher R. Somerville

Department of Biology, University of Saskatchewan, Saskatoon, SK, Canada S7N 0W0, MSU-DOE Plant Research Laboratory, Michigan State University, East Lansing, Michigan 48824

A mutant of Arabidopsis thaliana, two hundred times more resistant to the imidazolinone herbicide imazapyr than wild-type plants, was isolated by direct selection of seedlings from a mutagenized population. Genetic analysis showed that resistance is due to a single dominant nuclear mutation that could not be separated by recombination from a mutation in the CSR1 gene encoding acetohydroxy acid synthase. Acetohydroxy acid synthase activity in extracts isolated from the mutant was 1000-fold more resistant to inhibition by imazapyr than that of the wild type. The resistant enzyme activity cosegregated with whole plant resistance. These data strongly suggest that the mutation is an allele of CSR1 encoding an imazapyr-resistant AHAS.

1 This work was supported in part by grants from the Natural Science and Engineering Research Council of Canada (No. OGP0036718) and a grant from the National Science Foundation (No. PCM8351595).




This article has been cited by other articles:


Home page
 Proc. Natl. Acad. Sci. USAHome page
J. A. McCourt, S. S. Pang, J. King-Scott, L. W. Guddat, and R. G. Duggleby
Herbicide-binding sites revealed in the structure of plant acetohydroxyacid synthase
PNAS, January 17, 2006; 103(3): 569 - 573.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
G. Jander, S. R. Baerson, J. A. Hudak, K. A. Gonzalez, K. J. Gruys, and R. L. Last
Ethylmethanesulfonate Saturation Mutagenesis in Arabidopsis to Determine Frequency of Herbicide Resistance
Plant Physiology, January 1, 2003; 131(1): 139 - 146.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ASPB Publications PLANT PHYSIOLOGY® THE PLANT CELL
Copyright © 1990 by the American Society of Plant Biologists