Plant Physiol.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
 QUICK SEARCH:   [advanced]


     


Plant Physiology Preview
Published on January 11, 2006; 10.1104/pp.105.074906


This Article
Right arrow Full Text (Plant Physiology Preview (PDF))
Right arrow All Versions of this Article:
140/2/681    most recent
pp.105.074906v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Web of Science (17)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Yamamizo, C.
Right arrow Articles by Yoshioka, H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Yamamizo, C.
Right arrow Articles by Yoshioka, H.
Agricola
Right arrow Articles by Yamamizo, C.
Right arrow Articles by Yoshioka, H.

Received November 30, 2005
Returned for revision December 16, 2005
Accepted December 16, 2005

Rewiring Mitogen-Activated Protein Kinase Cascade by Positive Feedback Confers Potato Blight Resistance

Chihiro Yamamizo , Kazuo Kuchimura , Akira Kobayashi , Shinpei Katou , Kazuhito Kawakita , Jonathan D. G. Jones , Noriyuki Doke , and Hirofumi Yoshioka *

Graduate school of Bioagricultural Sciences, Nagoya University, Chikusa, Nagoya 464-8601, Japan
Department of Upland Agriculture, National Agricultural Research Center of Hokkaido Region, Memuro, Hokkaido 082-0071, Japan
Sainsbury Laboratory, John Innes Centre, Colney Lane, Norwich NR4 7UH, United Kingdom

* Corresponding author; email: hyoshiok{at}agr.nagoya-u.ac.jp.

Late blight, caused by the notorious pathogen Phytophthora infestans, is a devastating disease of potato (Solanum tuberosum) and tomato (Lycopersicon esculentum), and during 1840s caused the Irish potato famine and over one million fatalities. Currently grown potato cultivars lack adequate blight tolerance. Earlier cultivars bred for resistance used disease resistance (R) genes that confer immunity only to some strains of the pathogen harboring corresponding avirulence (Avr) gene. Specific R-mediated immunity and chemical controls are rapidly overcome in the field when new pathogen races arise through mutation, recombination or migration from elsewhere. A mitogen-activated protein kinase (MAPK) cascade plays a pivotal role in plant innate immunity. Here we show that the transgenic potato plants that carry a constitutively active form of MAPK kinase (MAPKK) driven by a pathogen-inducible promoter of potato, showed high resistance to early blight pathogen Alternaria solani as well as P. infestans. The pathogen attack provoked defense-related MAPKs activation followed by induction of NADPH oxidase gene expression, which is implicated in reactive oxygen species production, and resulted in hypersensitive response (HR)-like phenotype. We propose that enhancing disease resistance through altered regulation of plant defense mechanisms should be more durable and publicly acceptable than engineering overexpression of antimicrobial proteins.




This article has been cited by other articles:


Home page
Plant CellHome page
S. Tanaka, N. Ishihama, H. Yoshioka, A. Huser, R. O'Connell, G. Tsuji, S. Tsuge, and Y. Kubo
The Colletotrichum orbiculare ssd1 Mutant Enhances Nicotiana benthamiana Basal Resistance by Activating a Mitogen-Activated Protein Kinase Pathway
PLANT CELL, August 1, 2009; 21(8): 2517 - 2526.
[Abstract] [Full Text] [PDF]


Home page
Plant CellHome page
S. Asai, K. Ohta, and H. Yoshioka
MAPK Signaling Regulates Nitric Oxide and NADPH Oxidase-Dependent Oxidative Bursts in Nicotiana benthamiana
PLANT CELL, May 1, 2008; 20(5): 1390 - 1406.
[Abstract] [Full Text] [PDF]


Home page
J. Gen. Virol.Home page
L. Kiraly, Y. M. Hafez, J. Fodor, and Z. Kiraly
Suppression of tobacco mosaic virus-induced hypersensitive-type necrotization in tobacco at high temperature is associated with downregulation of NADPH oxidase and superoxide and stimulation of dehydroascorbate reductase
J. Gen. Virol., March 1, 2008; 89(3): 799 - 808.
[Abstract] [Full Text] [PDF]


Home page
Plant Physiol.Home page
I. J.E. Stulemeijer, J. W. Stratmann, and M. H.A.J. Joosten
Tomato Mitogen-Activated Protein Kinases LeMPK1, LeMPK2, and LeMPK3 Are Activated during the Cf-4/Avr4-Induced Hypersensitive Response and Have Distinct Phosphorylation Specificities
Plant Physiology, July 1, 2007; 144(3): 1481 - 1494.
[Abstract] [Full Text] [PDF]


Home page
Plant CellHome page
M. Kobayashi, I. Ohura, K. Kawakita, N. Yokota, M. Fujiwara, K. Shimamoto, N. Doke, and H. Yoshioka
Calcium-Dependent Protein Kinases Regulate the Production of Reactive Oxygen Species by Potato NADPH Oxidase
PLANT CELL, March 1, 2007; 19(3): 1065 - 1080.
[Abstract] [Full Text] [PDF]


Home page
Plant Physiol.Home page
C. Pignocchi, G. Kiddle, I. Hernandez, S. J. Foster, A. Asensi, T. Taybi, J. Barnes, and C. H. Foyer
Ascorbate Oxidase-Dependent Changes in the Redox State of the Apoplast Modulate Gene Transcript Accumulation Leading to Modified Hormone Signaling and Orchestration of Defense Processes in Tobacco
Plant Physiology, June 1, 2006; 141(2): 423 - 435.
[Abstract] [Full Text] [PDF]




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
ASPB Publications PLANT PHYSIOLOGY® THE PLANT CELL
Copyright © 2006 by the American Society of Plant Biologists