Plant Physiology Preview
Published on January 4, 2008; 10.1104/pp.107.113654
OPEN ACCESS ARTICLE
Received November 27, 2007
Accepted December 24, 2007
Two Class XI Myosins Function in Organelle Trafficking and Root Hair Development in Arabidopsis thaliana
Valera V. Peremyslov , Alexey I. Prokhnevsky , Dror Avisar , and Valerian V. Dolja *
Department of Botany and Plant Pathology and Center for Genome Research and Biocomputing, Oregon State University, Corvallis, Oregon 97331
* Corresponding author; email: doljav{at}science.oregonstate.edu.
Multigene families encoding class XI myosins are conserved in higher plants, however, little information is available on specific functions of these ubiquitous molecular motors. We isolated gene knockout mutants for all thirteen class XI myosins present in Arabidopsis thaliana genome. Inactivation of 11 myosin genes resulted in no discernible phenotypes under the normal growth conditions. In contrast, the knockouts of the remaining two myosin genes, XI-2 (formerly MYA2) and XI-K, exhibited similar defects in root hair elongation suggesting that the myosin-driven motility plays a significant role in a polar tip growth. Strikingly, inactivation of each of these myosins also reduced trafficking of Golgi stacks, peroxisomes and mitochondria in root hairs and in leaf epidermal cells. These results indicate that myosins XI-K and XI-2 play major and overlapping roles in the cell dynamics in Arabidopsis and highlight the redundant nature of myosin function in plants.
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