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Bioinformatics

Munich Information Center for Protein Sequences Plant Genome Resources. A Framework for Integrative and Comparative Analyses^1,[w]

Technische Universität München, Chair of Genome Oriented Bioinformatics, Center of Life and Food Science, D–85354 Freising-Weihenstephan, Germany (H.S., M.S.); and Institute for Bioinformatics, GSF National Research Center for Environment and Health, D–85764 Neuherberg, Germany (H.S., M.S., L.Y., R.E., H.G., D.H., G.H., K.F.X.M.)

With several plant genomes sequenced, the power of comparative genome analysis can now be applied. However, genome-scale cross-species analyses are limited by the effort for data integration. To develop an integrated cross-species plant genome resource, we maintain comprehensive databases for model plant genomes, including Arabidopsis (Arabidopsis thaliana), maize (Zea mays), Medicago truncatula, and rice (Oryza sativa). Integration of data and resources is emphasized, both in house as well as with external partners and databases. Manual curation and state-of-the-art bioinformatic analysis are combined to achieve quality data. Easy access to the data is provided through Web interfaces and visualization tools, bulk downloads, and Web services for application-level access. This allows a consistent view of the model plant genomes for comparative and evolutionary studies, the transfer of knowledge between species, and the integration with functional genomics data.

² Present address: Max Planck Institute for Plant Breeding Research, D–50829 Cologne, Germany.

^[w] The online version of this article contains Web-only data.

www.plantphysiol.org/cgi/doi/10.1104/pp.104.059188.

^* Corresponding author; e-mail schoof{at}mpiz-koeln.mpg.de; fax 49–221–5062–413.

Received January 5, 2005; returned for revision April 6, 2005; accepted May 3, 2005.

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