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On the Cover: The cover picture is a collage of images of three algae that are being developed as strong genomic systems, placed over the fluorescence image of a microarray that was used to elucidate sulfur-deprivation responses in Chlamydomonas reinhardtii. In this issue, microarrays have been used to study the impact of a nuclear-encoded protein required for petD mRNA accumulation in C. reinhardtii on the stability of other RNAs of plastial, mitochondrial, and nuclear origin (pp. 534-544). The two algal images at the top are from experiments in which the C. reinhardtii putative transcription factor PSR1, which controls many of the responses of this alga to phosphorus limitation, was immunolocalized to the nucleus. The bottom two images depict the targeting of GFP to the endoplasmic reticulum (left) and plastids (right) of the pennate diatom Phaeodactylum tricornutum. The image in the center is a scanning electron micrograph of the centric diatom Thalassiosira pseudonana, for which a full genome sequence has recently become available. Pennate and centric diatoms define the two major types of diatoms. Results reported in this issue through an extensive ESTapproach performed with P. tricornutum highlight the similarities and differences between these two groups and their distant red and green algal relatives (pp. 500-513). Cover design and preparation were by Arthur Grossman with image contributions from Nils Kroeger, Kirk Apt, Anton Montsant, and Chris Bowler.
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