Table II.

Calculated Ki values of recombinant Pt4CL1 and Pt4CL2

ProteinSubstrateInhibitor
PACAFA
μM
Pt4CL1PA  –4.37 ± 0.7099.83 ± 13.60
CA148.09 ± 18.09  –119.84 ± 16.03
FA52.87 ± 5.664.17 ± 0.20  –
Pt4CL2PA  –12.36 ± 0.85301.78 ± 19.66
CA4.30 ± 0.30  –242.83 ± 22.57
FA2.84 ± 0.426.61 ± 0.61  –

Values represent the mean ± sd of three independent assays.