Table I.

Transmembrane span prediction programs

ProgramWeb SiteReference
TmHMM 2.0 http://www.cbs.dtu.dk/services/TMHMM/ Sonnhammer et al. (1998)
HmmTop 2.0 http://www.enzim.hu/hmmtop Tusnady and Simon (1998, 2001)
SosuiG 1.1 http://sosui.proteome.bio.tuat.ac.jp Hirokawa et al. (1998)
Eiconda 0.9Not availableR. Schwacke (unpublished data)
TMPred http://www.ch.embnet.org/software/TMPRED_form.html Hofmann and Stoffel (1993)
TMap http://www.mbb.ki.se/tmap/ Persson and Argos (1994, 1996)
TopPred 2.0 http://bioweb.pasteur.fr/seqanal/interfaces/toppred.html von Heijne (1992); Claros and von Heijne (1994)