Table III.

Kinetic constants for UGT74M1 and various sapogenins substrates

See “Materials and Methods” for details.

SubstrateEmbedded ImageEmbedded ImageEmbedded Image
Gypsogenic acida1701.136.5 × 103
16-OH gypsogenic acid511.292.5 × 104
Gypsogenin420.1253.0 × 103
Quillaic acid370.1113.0 × 103
  • a Constants for gypsogenic acid are considered estimates, because solubility limited the maximum concentration used to 100 μm.