Table I.

Effects of various nucleotide triphosphates and nucleotide monophosphates on genistein transport

Plasma membrane vesicles were incubated with 100 μm genistein in the presence of 5 mm of the respective compounds listed in the table. Values shown are mean ± sd of three replicates, and asterisks indicate a statistically significant difference compared to the −MgATP control. **, P < 0.01; *, P < 0.05.

CompoundGenistein Uptake
%
−MgATP21.8 ± 1.8
+MgGTP48.3 ± 12.4*
+MgTTP55.3 ± 7.3*
+MgCTP50.4 ± 5.9*
+MgATP-γ-S28.5 ± 4.2
+MgAMP24.2 ± 2.9
+MgCMP20.3 ± 3.3
+MgATP (positive control)100**