Table II.

Protein phosphatase summary data

Human protein phosphatase sequences were used as queries, and candidate homolog sequences were obtained and analyzed, as detailed in “Materials and Methods”. Protein phosphatase classes are modeled after the scheme used in Moorhead et al. (2007). The number of candidate homologs is given for each species and protein phosphatase class, not including splice variants. Where appropriate, further subdivision is made of classes into sequence cluster subgroups. Details of findings are given in “Results”.

Protein Phosphatase FamilySequence ClusterHumanC. reinhardtiiO. tauriP. trichocarpaArabidopsisO. sativaAlgae versus Othersa
PTP superfamily (CX5R)
    Class I PTPSSU72s111111P-Lb
    Class I PTP (DSPs)Slingshots3NoneNoneNoneNoneNoneP-L
    Class I PTP (DSPs)CDC14s21NoneNoneNoneNoneBoth
    Class II PTPCDC25s3None1NoneNoneNoneBoth
    Class III PTPLMWPTP11None211Same
Asp-based catalysis (DXDXT/V)
    FCP-likeSCP FCP1-like tree group A31c1cNoneNoneNoneA-L
    FCP-likeFCP1-like tree groups B–G3521279Both
    FCP-like“FCP Assemblage” FCP-like tree group H1332d72P-L
    FCP-likeFCP-like tree group INone1e2323P-L
    FCP-likeFCP-like tree group J111211A-L
    FCP-likeFCP1-like CPL1,2sNoneNoneNone424A-L
    HAD familyEYAs4NoneNone111Neither
    HAD familyChronophins132332A-Lf
  • a Similarity of algal sequence number/affinity to plant sequences (P-L, plant-like); animal sequences (A-L, animal-like); both plant and animal sequences (Both); all organisms equivalent (Same); or algae similar to neither plants nor animals (Neither).

  • b Algal proteins cluster with the plant homologs.

  • c Algal SCP-like proteins do not have the same bootstrap support as the animal proteins; see “Results” for details.

  • d Protein pop560900 is included with both the FCP proteins and CPL1 and CPL2 proteins for the phylogenetic trees, but is only counted with CPL1 and CPL2.

  • e Cre166215 may be included in either Unclassified or Group I, depending on the tree inference method chosen (here included with Group I).

  • f Algal chronophins are plant like in that there are multiple proteins, but the sequences that can be assigned an affinity are animal like.