Table II.

Summary of inhibitory activity (IC50a) of KTIs against different proteases

KTITrypsinChymotrypsinElastaseSubtilisinPapain
μm
TI20.02802.95NANANA
TI30.1520.15274.1NANA
TI41280.294NANANA
TI50.2050.1889.16NANA
TI60.6430.1110.731NANA
GmKTI0.01160.05673.65NANA
  • a ICs were calculated from the linear portion of the plot of residual proteinase activity against TI protein concentration (Fig. 7). NA, No activity.