Table III.

Regulatory analysis of E2Fa/OBP1 target genes

Features:OBP1_UPOBP1_DOWNE2Fa_UPE2Fa_DOWNOBP1/E2Fa_UP
No. of Genes:63284241222065a
Cell cycle-modulated expression
    G1913232
    S3852701312
    G2419010
    M1143303
Enrichment GOb
    GO:0006260 DNA replication6.6x (2.83E-06)24.2x (8.59E-36)55.9x (4.90E-19)
    GO:0007017 microtubule-based process9.9x (2.61E-13)
    GO:0042545 cell wall modification4.3x (3.52E-03)
    GO:0009607 response to biotic stimulus2.5x (5.87E-09)
Enrichment cis-regulatory elementsc
    GCGGGAAN (E2F)3% (9.97E-06)15% (4.19E-65)26% (1.11E-20)
    WTTSSCSS (E2F PLACE)55% (3.16E-37)74% (4.72E-14)
    TAAAG (DOF PLACE)94% (4.45E-04)
    GACCGTTN (MSA)7% (6.64E-30)
    CTTATCCN (Ibox)4% (4.56E-05)
    CCATGTGN (MYCATERD1)3% (1.95E-04)
    ANCACATG (MYCATRD22)6% (2.02E-07)
  • a Overlap significantly larger than expected by chance (P value < 3.50E-27).

  • b Enrichment fold (P value).

  • c Fraction of genes with motif (P value).